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Table 1 The analysis of the IC50 and RI of MCF-7 and MCF-7/ADR cells towards ADMh

From: Knockdown of SALL4 inhibits the proliferation and reverses the resistance of MCF-7/ADR cells to doxorubicin hydrochloride

Intervention time/h

IC50 (uM)

Resistance index (RI)

MCF-7

MCF-7/ADR

MCF-7/ADR

CON

Lv-shNC

Lv-shSALL4

CON

Lv-shNC

Lv-shSALL4

24

1.06 ± 0.09

152.57 ± 2.33

149.03 ± 3.28

42.09 ± 3.42**

143.93 ± 2.20

140.60 ± 3.60

39.70 ± 33.23**

48

0.22 ± 0.01

29.66 ± 1.14

30.01 ± 1.88

6.48 ± 0.42**

134.82 ± 5.17

136.41 ± 5.40

29.63 ± 1.59**

  1. Lv-shSALL4 group vs. CON group
  2. ** P < 0.01