Fig. 5

Sequence features comparisons between different exon sets identify characteristics of TG003 skip-enhanced exons. Box plots of scores of sequence features of control homologous exon pairs (n = 2335) and human TG003 skip-enhanced and their insensitive mouse counterpart exon pairs (n = 21). Median is shown by bold horizontal line and boxes are drawn between the third quartile (top of box) and first quartile (bottom of box). Outliers are either three times interquartile range or more above the third quartile, or three times interquartile range or more below the first quartile, and are not shown in the plot. The maximum and minimum are shown with the whiskers. (*) indicates p value <0.05, and (**) p value <0.01, (***) p value <0.001, calculated by Wilcoxon rank sum test