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Figure 5 | BMC Molecular Biology

Figure 5

From: Mechanical stimulation of human tendon stem/progenitor cells results in upregulation of matrix proteins, integrins and MMPs, and activation of p38 and ERK1/2 kinases

Figure 5

Western blotting analysis for collagen-binding integrins, integrin-downstream kinases and matrix metalloproteinases upon 8% mechanical stimulation of TSPC. (A) Collagen I-binding integrins α1, α2 and α11 (ratio to GAPDH protein expression); (B) Phosphorylated and total levels of FAK, ERK, Akt, p38 and Jnk (ratio phospho-/total protein); (C) MMP9, 13 and 14 (ratio to GAPDH). (D) Schematic summary of the changes occurring in TSPC upon 8% biaxial mechanical loading. Data is representative of 3 donors, each used in 3 independent experiments; *p < 0.1, **p < 0.05, ***p < 0.01.

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BMC Molecular Biology

ISSN: 1471-2199

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