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Figure 2 | BMC Molecular Biology

Figure 2

From: Mechanical stimulation of human tendon stem/progenitor cells results in upregulation of matrix proteins, integrins and MMPs, and activation of p38 and ERK1/2 kinases

Figure 2

Expression of mechanoresponsive and extracellular matrix genes upon mechanical stimulation of TSPC. (A) RT-PCR for c-fos and HB-GAM expression changes after 1 and 3 days stimulation with 1, 5 and 8% mechanical stress. PCR densitometric quantification is shown as fold changes to the unstimulated controls; *p < 0.1, **p < 0.05, ***p < 0.01. (B) RT-PCR analysis for collagen 1 and 3, and tendon-related proteoglycans (COMP, decorin, tenascin C, biglycan, fibromodulin, lumican and versican). Data is representative of 3 donors, each used in 3 independent experiments.

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BMC Molecular Biology

ISSN: 1471-2199

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