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Table 1 IL-12 cytokine levels in the supernatants of electroporated DCs

From: Ectopic expression of a truncated CD40L protein from synthetic post-transcriptionally capped RNA in dendritic cells induces high levels of IL-12 secretion

 

IL-12, pg/mL

 

cellular material used

CD40L WT

CD40L DXE

*Fold change

donor 1

326

8068

24.7

donor 2

31076

133712

4.3

donor 3

5717

35796

6.3

donor 4

2417

36572

15.1

donor 5

8085

58532

7.2

donor 6

7207

20954

2.9

  1. *fold-increase in IL-12 detected by Elisa in DC supernatants 24 hrs post electroporation with CD40LDXE RNA compared to WT RNA