Optimal alignment of C. neoformans myo -inositol oxygenase to the Mus musculus myo -inositol oxygenase. MIOX1, MIOX2 and MIOX3 refers to the C. neoformans myo-inositol oxygenase protein isoforms. The predicted consensus secondary structure for each sequence is below the respective amino acid. Helices are represented by h and are in red. Sheets are represented by s and are in green. Each protein is predicted to have 10 helices and four sheets. Conserved amino acids essential to enzyme function are highlighted in blue.