TY - JOUR AU - Mackenzie, Emalee A. AU - Klig, Lisa S. PY - 2008 DA - 2008/10/14 TI - Computational modeling and in silico analysis of differential regulation of myo-inositol catabolic enzymes in Cryptococcus neoformans JO - BMC Molecular Biology SP - 88 VL - 9 IS - 1 AB - Inositol is a key cellular metabolite for many organisms. Cryptococcus neoformans is an opportunistic pathogen which primarily infects the central nervous system, a region of high inositol concentration, of immunocompromised individuals. Through the use of myo-inositol oxygenase C. neoformans can catabolize inositol as a sole carbon source to support growth and viability. SN - 1471-2199 UR - https://doi.org/10.1186/1471-2199-9-88 DO - 10.1186/1471-2199-9-88 ID - Mackenzie2008 ER -