TY - JOUR AU - Grahnert, Andreas AU - Richter, Steffi AU - Siegert, Fritzi AU - Berndt, Angela AU - Hauschildt, Sunna PY - 2008 DA - 2008/10/14 TI - The orthologue of the "acatalytic" mammalian ART4 in chicken is an arginine-specific mono-ADP-ribosyltransferase JO - BMC Molecular Biology SP - 86 VL - 9 IS - 1 AB - Human ART4, carrier of the GPI-(glycosyl-phosphatidylinositol) anchored Dombrock blood group antigens, is an apparently inactive member of the mammalian mono-ADP-ribosyltransferase (ART) family named after the enzymatic transfer of a single ADP-ribose moiety from NAD+ to arginine residues of extracellular target proteins. All known mammalian ART4 orthologues are predicted to lack ART activity because of one or more changes in essential active site residues that make up the R-S-EXE motif. So far, no other function has been detected. SN - 1471-2199 UR - https://doi.org/10.1186/1471-2199-9-86 DO - 10.1186/1471-2199-9-86 ID - Grahnert2008 ER -