Table 2 Transcription factor family members
From: New insights into SRY regulation through identification of 5' conserved sequences
Family | Transcription factors |
|---|---|
BRNF | Brn POU domain factors |
|  |    BRN2/3/4/5 |
OCT1 | Octamer binding protein |
|  |    OCT1/2/3 |
HOXF | Factors with moderate activity to homeodomain consensus sequence |
|  |    Barx2, CRX, GSC, Gsh-1/2, HOX1, HOXA9, HOXB9, HOXC13, NANOG, OTX2, PCE1, PHOX2a/2b, PTX1 pituitary homeobox. |
PARF | PAR/bZIP family |
|  |    DBP Albumin D-box binding protein, HLF hepatic leukemia factor, TEF Thyrotrophic embryonic factor, VBP PAR-type chicken vitellogenin promoter binding protein. |
FKHD | Fork head domain factors |
|  |    FHXA/B, FKHRL1 (FOXO), FREAC2/3/4/7 fork head related activators (FOXF2, FOXC1, FOXD1, FOXL1), HFH1/2/3/8 (FOXQ1, FOXD3, FOXI1, Freac-6. FXF1), HNF3B (FOXA2), IlF1 (FOXK2), XFD1/2/3. |
GATA | GATA binding factors |
|  |    GATA, GATA1/2/3. |
CREB | Camp-responsive element binding proteins |
|  |    ATF, ATF2/6 activation transcription factors, c-Jun/ATF2 heterodimers, CREB, CREB1/2, CREB2/cJun, E4BP4, TAX/CREB complex, XBP1 X-box-binding protein. |
CDXF | Vertebrate caudal related homeodomain Protein |
|  |    CDX1/2 Intestine specific homeodomain factor and mammalian caudal related intestinal TF. |
SRFF | Serum response element binding factor |
|  |    SRF.01/02/03 |
MEF2 | Myocyte-specific enhancer binding Factor |
|  |    MEF2, RSRFC4 related to serum response factor, SL1 member of RSRF |
ETSF | Human and murine ETS1 factors |
|  |    c-Ets-1/2(p54), ELF-2(NERF1a), ELK1, FLI, GABP GA binding protein, GABPB1 GA repeat binding protein beta 1, NRF2 nuclear respiratory factor 2, PDEF Prostate-derived Ets factor, PEA3 polyomavirus enhancer A binding protein 3, ETV4, PU1, SPI1, SpiB. |
HNF1 | Hepatic nuclear factor 1 |
|  |    HNF1 |
SORY | SOX/SRY-sex/testis determining and related HMG box factors |
|  |    HBP1, HMGA1/2, HMGIY, SOX5/9, SRY. |
NKXH | NKX homeodomain factors |
|  |    Hmx2/Nkx5-2 homeodomain transcription factor, NKX31 prostate-specific homeodomain protein, TTF1 thyroid transcription factor |
LHXF | Lim homeodomain factors |
|  |    LHX3 and LMXB1 |
MYT1 | MYT1 C2HC zinc finger protein |
|  |    MyT1 myelin transcription factor, and MyT1L. |
PLZF | C2H2 zinc finger protein |
|  |    PLZF promyelocytic leukemia zinc finger (TF with 9 Kruppel-like zinc fingers) |
NFKB | Nuclear factor kappa B/c-rel |
|  |    NF-kappaB (p50 and p65), HIVEP1; ZAS Domain TF human immunodeficiency virus type 1 enhancer-binding protein-1 (HIVEP1), major histocompatibility complex-binding protein-1 (MBP-1), positive regulatory domain II-binding factor (PRDII-BF1) |
EVI1 | Myleoid transforming protein |
|  |    EVI1 ecotropic viral integration site 1 encoded factor, amino-terminal zinc finger domain. MEL1 (MDS1/EVI1-like gene 1) DNA-binding domain 1. |
TBPF | TATA-binding protein factors |
|  |    ATATA avian C-type LTR TAT box, LTATA Lentivirus LTR TAT box, MTATA muscle TATA box, TATA cellular and viral TATA box elements, and Mammalian C-type LTR TATA box. |
HOXC | HOX – PBX complexes |
|  |    HOX/PBX binding sites, PBX1, PBX-HOXA9 binding site. |
GFI1 | Growth factor independence transcriptional Repressor |
|  |    GFI1.01/02, GFI1B.01. |
PITI | GHF-1 pituitary specific pou domain TF |
|  |    Pit1, GHF1. |
OCTP | OCT1 binding factor (POU-specific domain) |
|  |    OCT1P Octamer-binding factor 1, POU-specific domain) |
RORA | v-ERB and RAR-related orphan receptor alpha |
|  |    REV-ERBA orphan nuclear receptor rev-erb alpha (NR1D1), RORA/RORA1/2 RAR-related orphan receptor alpha/1/2, RORGAMMA RAR-related orphan receptor gamma, VERBA viral homolog of thyroid hormone receptor alpha1 |
HAML | Human acute myelogenous leukemia factors |
|  |    AML1/CBFA2 Runt domain binding site, AML3 runt-related transcription factor 2/CBFA1 |
RBPF | RBPJ kappa |
|  |    Mammalian transcriptional repressor RBP-Jkappa/CBF1 |
IRFF | Interferon regulatory factors |
|  |    IRF1/2/3/4(NF-EM5, PIP, LSIRF, ICSAT)/7, ISRE interferone stimulated response element. |
PAX6 | PAX-4/PAX-6 paired domain binding sites |
|  |    PAX4 and PAX6 paired domain binding site |
MZF1 | Myeloid zinc finger 1 factors |
|  |    MZF1 |
GZF1 | GDNF-inducible zinc finger gene 1 |
|  |    GZF1 (ZNF336) |
ZFHX | Two-handed zinc finger homeodomain transcription factors |
|  |    AREB6 (Atp1a1 regulatory element binding factor 6), deltaEF1 (Delta-crystallin enhancer binding factor, transcription factor 8, zinc finger homeobox 1a), SIP1 (Smad-interacting protein) |
PLAG | Pleomorphic adenoma gene |
|  |    (PLAG) 1, a developmentally regulated C2H2 zinc finger protein |
MOKF | Mouse Kruppel like factors |
|  |    MOK2.01/02 Ribonucleoprotein associated zinc finger protein MOK-2 |
HOMF | Homeodomain transcription factors |
|  |    DLX1/2/5, Distal-less 3, EN1 homeobox protein engrailed, HHEX, MSX1/2, NOBOX, S8. |
RBIT | Regulator of B-Cell IgH transcription |
|  |    Bright, B cell regulator of IgH transcription |
SATB | Special AT-rich sequence binding |
|  |    Protein SATB1 |
CLOX | CLOX and CLOX homology (CDP) factors |
|  |    CDP cut-like homeodomain protein, transcriptional repressor CDP, CDPCR3, CDPCR3HD, CLOX, CUT2. |