Table 1 C/EBPδ Target gene functional categories
Signal transduction | Â | Â |
|---|---|---|
Gene Name | Gene Description | Gene ID |
   ADM | Adrenomedullin | 133 |
   BAI3 | brain-specific angiogenesis inhibitor 3 | 577 |
   DTNA | dystrobrevin, alpha | 1837 |
   DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 1857 |
   EDG1 | endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 | 1901 |
   GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | 2790 |
   IRAK2 | interleukin-1 receptor-associated kinase 2 | 3656 |
   LOX | lysyl oxidase | 4015 |
   NPAS1 | neuronal PAS domain protein 1 | 4861 |
   CCL25 | chemokine (C-C motif) ligand 25 | 6370 |
   CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 8476 |
   INTS6 | integrator complex subunit 6 | 26512 |
   GTPBP2 | GTP binding protein 2 | 54676 |
   EPS15L2 | epidermal growth factor receptor pathway substrate 15-like 2 | 55380 |
   VAC14 | Vac14 homolog (S. cerevisiae) | 55697 |
   ERBB2IP | erbb2 interacting protein | 55914 |
   ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) | 64221 |
   C9orf89 | chromosome 9 open reading frame 89 | 84270 |
   SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 | 90864 |
   HSP90AA1 | heat shock protein 90 kDa alpha (cytosolic), class A member 1 | 3320 |
   FGF9 | fibroblast growth factor 9 (glia-activating factor) | 2254 |
   SCAP2 | src family associated phosphoprotein 2 | 8935 |
   GPR160 | G protein-coupled receptor 160 | 26996 |
   VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 7421 |
Metabolism | Â | Â |
   OXA1L | oxidase (cytochrome c) assembly 1-like | 5018 |
   RPP30 | ribonuclease P/MRP 30 kDa subunit | 10556 |
   THBS4 | thrombospondin 4 | 7060 |
   CKAP1 | cytoskeleton associated protein 1 | 1155 |
   DLD | dihydrolipoamide dehydrogenase | 1738 |
   ESD | esterase D/formylglutathione hydrolase | 2098 |
   LRP1 | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 4035 |
   PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | 5689 |
   RPL29 | ribosomal protein L29 | 6159 |
   MTMR6 | myotubularin related protein 6 | 9107 |
   ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 11096 |
   GCAT | lycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase) | 23464 |
   ADAT1 | adenosine deaminase, tRNA-specific 1 | 23536 |
   FLRT2 | fibronectin leucine rich transmembrane protein 2 | 23768 |
   MRPL35 | mitochondrial ribosomal protein L35 | 51318 |
   OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 55611 |
   USP48 | ubiquitin specific peptidase 48 | 84196 |
   ACBD5 | acyl-Coenzyme A binding domain containing 5 | 91452 |
   C9orf103 | chromosome 9 open reading frame 103 | 414328 |
   GANC | glucosidase, alpha; neutral C | 2595 |
   BCAT2 | branched chain aminotransferase 2, mitochondrial | 587 |
   CRLF3 | cytokine receptor-like factor 3 | 51379 |
   ADPRH | ADP-ribosylarginine hydrolase | 141 |
Transcriptional regulation | Â | Â |
   KLF6 | Kruppel-like factor 6 | 1316 |
   DBP | D site of albumin promoter (albumin D-box) binding protein | 1628 |
   FLI1 | Friend leukemia virus integration 1 | 2313 |
   MEF2B | MADS box transcription enhancer factor 2, polypeptide B | 4207 |
   POLR2F | polymerase (RNA) II (DNA directed) polypeptide F | 5435 |
   POU2F1 | POU domain, class 2, transcription factor 1 | 5451 |
   SOX4 | SRY (sex determining region Y)-box 4 | 6659 |
   TBP | TATA box binding protein | 6908 |
   ZNF20 | zinc finger protein 20 | 7568 |
   CSDA | cold shock domain protein A | 8531 |
   RFXANK | regulatory factor X-associated ankyrin-containing protein | 8625 |
   TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A | 9015 |
   SSBP2 | single-stranded DNA binding protein 2 | 23635 |
   MKL2 | MKL/myocardin-like 2 | 57496 |
   TGIF2 | TGFB-induced factor 2 (TALE family homeobox) | 60436 |
   IRX6 | iroquois homeobox protein 6 | 79190 |
   ESX1 | extraembryonic, spermatogenesis, homeobox 1 homolog (mouse) | 80712 |
   ZNF573 | zinc finger protein 573 | 126231 |
   ALX4 | aristaless-like homeobox 4 | 60529 |
Transporters | Â | Â |
   KCND2 | potassium voltage-gated channel, Shal-related subfamily, member 2 | 3751 |
   PCM1 | pericentriolar material 1 | 5108 |
   TUSC3 | tumor suppressor candidate 3 | 7991 |
   SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 9016 |
   HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 9146 |
   HCN4 | hyperpolarization activated cyclic nucleotide-gated potassium channel 4 | 10021 |
   SLC40A1 | solute carrier family 40 (iron-regulated transporter), member 1 | 30061 |
   MCART1 | mitochondrial carrier triple repeat 1 | 92014 |
   CCBE1 | collagen and calcium binding EGF domains 1 | 147372 |
Cell cycle regulation | Â | Â |
   SEPT7 | septin 7 | 989 |
   RCC1 | regulator of chromosome condensation 1 | 1104 |
   PAPD5 | PAP associated domain containing 5 | 64282 |
   DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 9077 |
DNA binding | Â | Â |
   TOP2B | topoisomerase (DNA) II beta 180 kDa | 7155 |
   HIST1H4F | histone 1, H4f | 8361 |
   KCMF1 | potassium channel modulatory factor 1 | 56888 |
   XPC | xeroderma pigmentosum, complementation group C | 7508 |
   MSH5 | mutS homolog 5 (E. coli) | 4439 |
Cell Adhesion | Â | Â |
   GP5 | glycoprotein V (platelet) | 2814 |
   ITGB8 | integrin, beta 8 | 3696 |
   PCDH9 | Protocadherin 9 | 5101 |
   RSHL1 | radial spokehead-like 1 | 81492 |
   THBS4 | thrombospondin 4 | 7060 |
Apoptosis | Â | Â |
   TIA1 | cytotoxic granule-associated RNA binding protein | 7072 |
   BCL2L1 | BCL2-like 1 | 598 |
   RNF34 | ring finger protein 34 | 80196 |
Miscellaneous | Â | Â |
   HSPCA | heat shock protein 90 kDa alpha (cytosolic), class A member 1 | 3320 |
   OTOF | otoferlin | 9381 |
   LOH12CR1 | loss of heterozygosity, 12, chromosomal region 1 | 118426 |
   MYEOV2 | myeloma overexpressed 2 | 150678 |
   TMEM87A | transmembrane protein 87A | 25963 |
   MTPN | myotrophin | 136319 |
   DISC1 | disrupted in schizophrenia 1 | 27185 |