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Table 2 Biochemical data of three groups

From: Pioglitazone retrieves hepatic antioxidant DNA repair in a mice model of high fat diet

Group Chow diet (n = 5) High fat diet (n = 5) High fat diet + PioG (n = 5) P
Initial BW (gm) 21.1 ± 0.3 21.6 ± 0.4 20.8 ± 0.5 0.538
Final BW (gm) 24.8 ± 0.9 26.0 ± 0.9 27.6 ± 0.7 0.088
BW gain (gm) 3.7 ± 0.7 4.4 ± 0.8 5.0 ± 0.5 0.025
Blood glucose (mg/dl) 125.0 ± 8.0 169.2 ± 4.2 147.6 ± 7.2 0.011
Cholesterol (mg/dl) 59.5 ± 10.4 159.7 ± 37.1 151.6 ± 14.2 0.008
Triglyceride (mg/dl) 71.9 ± 17.1 102.8 ± 27.6 95.9 ± 13.0 0.355
ALT (IU/L) 14.8 ± 5.5 13.0 ± 5.9 27.7 ± 13.6 0.691
Hepatic TG (mg/g protein) 72.0 ± 19.9 177.5 ± 61.4 153.6 ± 60.9 0.023
MDA (nmol/mg protein) 5.9 ± 1.0 9.7 ± 0.8 5.5 ± 0.3 0.008
  1. Values are mean ± S.E.
  2. ALT: alanine aminotransferase; Hepatic TG: hepatic triglyceride content; MDA: malondialdehyde
  3. Kruskal-Wallis test were used for statistical analysis; p < 0.05 was indicated significant.