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Table 2 Biochemical data of three groups

From: Pioglitazone retrieves hepatic antioxidant DNA repair in a mice model of high fat diet

Group

Chow diet (n = 5)

High fat diet (n = 5)

High fat diet + PioG (n = 5)

P

Initial BW (gm)

21.1 ± 0.3

21.6 ± 0.4

20.8 ± 0.5

0.538

Final BW (gm)

24.8 ± 0.9

26.0 ± 0.9

27.6 ± 0.7

0.088

BW gain (gm)

3.7 ± 0.7

4.4 ± 0.8

5.0 ± 0.5

0.025

Blood glucose (mg/dl)

125.0 ± 8.0

169.2 ± 4.2

147.6 ± 7.2

0.011

Cholesterol (mg/dl)

59.5 ± 10.4

159.7 ± 37.1

151.6 ± 14.2

0.008

Triglyceride (mg/dl)

71.9 ± 17.1

102.8 ± 27.6

95.9 ± 13.0

0.355

ALT (IU/L)

14.8 ± 5.5

13.0 ± 5.9

27.7 ± 13.6

0.691

Hepatic TG (mg/g protein)

72.0 ± 19.9

177.5 ± 61.4

153.6 ± 60.9

0.023

MDA (nmol/mg protein)

5.9 ± 1.0

9.7 ± 0.8

5.5 ± 0.3

0.008

  1. Values are mean ± S.E.
  2. ALT: alanine aminotransferase; Hepatic TG: hepatic triglyceride content; MDA: malondialdehyde
  3. Kruskal-Wallis test were used for statistical analysis; p < 0.05 was indicated significant.