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Table 1 Body weights and plasma values of the four groups of rats under study

From: Genomic actions of 1,25-dihydroxyvitamin D3 on insulin receptor gene expression, insulin receptor number and insulin activity in the kidney, liver and adipose tissue of streptozotocin-induced diabetic rats

 

Control

1,25D 3

STZ

STZ + 1,25D 3

Final weight (g)

283 ± 1

290 ± 2a

242 ± 6ab

254 ± 3abc

Glucose (mg/dl)

125 ± 7

130 ± 2

420 ± 36ab

459 ± 16ab

Insulin (ng/ml)

1.6 ± 0.3

1.5 ± 0.2

0.7 ± 0.3ab

0.5 ± 0.1ab

25-Hydroxy-vitamin D 3 (ng/ml)

19 ± 1

15 ± 1

15 ± 3

17 ± 3

Calcium (mg/dl)

7.5 ± 1

10 ± 1

10 ± 0.4

11 ± 1a

Phosphorus (mg/dl)

6.8 ± 1

8.7 ± 1

7.2 ± 0.5

11 ± 0.7ac

Proteins (mg/dl)

65 ± 1

66 ± 1

63 ± 0.9

64 ± 1

  1. Sham-treated rats (Control), rats treated with 1,25D3 [150 IU/Kg (3.75 μg/Kg) one a day, for 15 days] (1,25D3), streptozotocin-induced diabetic rats (STZ) and streptozotocin-induced diabetic rats treated with 1,25D3 (STZ+1,25D3).
  2. Values are the mean ± SEM of 6–12 determinations in each group.
  3. a p < 0.05 vs. Control-rats; b p < 0.05 vs. 1,25D3-rats; c p < 0.05 vs. STZ-rats.