Figure 2

in silico analysis of ms1 putative promoter. (A) Phylogenetic comparative analysis of ms1 5'-region from Homo sapiens and Rattus norvegicus (reference sequence), as obtained by VISTA, setting ECR at ≥ 100 bp and conservation at ≥ 80%. (B) Alignment of ECR α and β, containing several putative transcription factor-binding sites, in Rattus norvegicus, Mus musculus, Bos taurus, Homo sapiens, Pan troglodytes and Macaca mulatta. Sequences were obtained from the ENSEMBL genome database and aligned using CLUSTAL W.