Figure 2

Comparative gene structure in teleost β2 subunits. A) The exons identified for each of four teleost β2 genes are listed vertically with indication of their size in bp. Exons on each horizontal line of the table are homologous in sequence (see later figures for alignments). Exons are color coded to indicate what portion of the 5-domain MAGUK protein (diagrammed in B) they comprise. ^ATG, indicates the presence of an initiation codon in the exon. *, indicates the exon contains a premature in-frame termination codon. C) Percent amino acid identity among vertebrate β2 subunits within the SH3 through GK sequences. D) The transcript variant numbers assigned to the alternatively spliced transcripts are listed on the left; transcript variant composition is depicted by exon numbers.