Figure 3

Mapping of CAGE tags to the human DYRK1A promoter. The CAGE database was searched for tags ascribed to the human DYRK1A gene (upper panel) and the murine Dyrk1a gene (lower panel) with the help of the CAGE basic viewer. All tags located within a region of 1,000 bp upstream of TSS B were selected, and the numbers of tags with 5'-ends at one specific nucleotide position were plotted vs. the position relative to TSS B. Major tag clusters (> 10 tags) as defined by Carninci et al. [39] are highlighted by coloring, and the number of tags forming this cluster is indicated. The region marked by a grey bar in the murine promoter was not sequenced in the genome sequence assembly (mouse May 2004) on which the CAGE tags were mapped.