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Table 1 Differential gene expression results in EMBs from DCM and DCMi patients related to HPRT-CCM and CDKN1B using T-PreAmp

From: Preamplification techniques for real-time RT-PCR analyses of endomyocardial biopsies

Gene DCM DCMi p value
CD3d 0.014163 ± 0.008761 0.045395 ± 0.015252 <0.0001
CD3z 0.043139 ± 0.010119 0.060631 ± 0.007718 0.0023
TRBC 0.015027 ± 0.010150 0.027622 ± 0.010532 0.0098
TRBV2 0.001487 ± 0.001300 0.004503 ± 0.002881 0.0053
TRBV4 0.001501 ± 0.001432 0.005441 ± 0.003850 0.0047
TRBV6 0.002926 ± 0.002154 0.005478 ± 0.002562 0.0307
TRBV10 0.000186 ± 0.000127 0.000905 ± 0.000967 0.0245
TRBV20 0.003935 ± 0.003140 0.019818 ± 0.018318 0.0105
TRBV23 0.000408 ± 0.000269 0.006402 ± 0.008324 0.0270
TRBV24 0.000282 ± 0.000265 0.004754 ± 0.006232 0.0075
TRBV29 0.001302 ± 0.001168 0.002815 ± 0.00138 0.0192
IL6 0.002020 ± 0.001246 0.004133 ± 0.002452 0.0094
TNFa 0.028511 ± 0.014230 0.052024 ± 0.017001 0.0049
CXCL14 0.151853 ± 0.145437 0.054158 ± 0.052000 0.0299
CX3CL1 0.96874 ± 0.431717 1.39651 ± 0.790158 0.0245
APN 0.390377 ± 0.555952 0.035850 ± 0.058782 0.0092
NFATC3 1.29493 ± 0.479396 2.56855 ± 0.776956 0.0052
CYR61 0.85785 ± 0.47640 2.94840 ± 2.33843 <.0001
TF 3.59608 ± 1.01046 2.14158 ± 0.53169 0.0109
T-bet 0.014431 ± 0.005826 0.022267 ± 0.008127 0.0355
Granzyme A 0.014704 ± 0.006914 0.035028 ± 0.011726 0.0004
Granzyme B 0.062487 ± 0.022406 0.105532 ± 0.026082 0.0027
Granulysin 0.206285 ± 0.186560 0.532339 ± 0.327002 0.0183
Eomesodermin 0.014428 ± 0.007246 0.036024 ± 0.007900 0.0011
av5b1 1.04571 ± 0.283760 1.71316 ± 0.844310 0.0033
GDF15 0.020984 ± 0.013187 0.041715 ± 0.028283 0.0127
CD62E 0.002714 ± 0.001093 0.012877 ± 0.008890 0.0119
  1. Significantly different gene expression (E; normalized to the housekeeping genes HPRT-CCM or CDKN1B) T-PreAmp real-time RT-PCR results in EMBs from DCM patients compared with EMBs from patients with immunohistologically confirmed DCMi (>7 CD3+ infiltrates/mm2). The values are given as means ± SD, followed by the respective p values in significantly different comparisons.