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Figure 4 | BMC Molecular Biology

Figure 4

From: Simultaneous targeted exchange of two nucleotides by single-stranded oligonucleotides clusters within a region of about fourteen nucleotides

Figure 4

Exchange rate of the second nucleotide. Percentage of clones with both exchanges after transfection with TA-clamp modified oligonucleotides carrying their first exchange nucleotide at hprt position 151. The X-axis indicates the distance of the second mismatch from the first exchange position in upstream and downstream direction.

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