Wnt3a stimulation of STF mediated by Fzd2 and Ror2 is inhibited by Dkk1 and Krm1. H441 cells were transfected with pSV-β-gal (Promega, WI), STF, Fzd2 and Ror2WT with and without Dkk1 and Krm1 expression constructs, and then treated with conditioned media, L-CM or Wnt3aCM. Equal amounts of DNA and conditioned media were used in each assay. Luciferase values were normalized to beta-galactosidase for transfection efficiency. Values of the assay transfected with control vector and treated with L-CM alone (empty bars) were adjusted to unity to normalize all other experimental values in the same group. * indicates p < 0.05.