BMC Molecular Biology

Table 2 Sub-cellular distribution of FGF and GFG immunoreactivity in rat tissues. Immunohistochemistry was performed as described in Materials and Methods. Tissues were scored as negative, -; a trace, (+); positive, +; or strongly positive, ++.

From: Alternative splicing and differential subcellular localization of the rat FGF antisense gene product

Tissue		Subcellular Distribution
		FGF		GFG
		Cyt	Nuc	Cyt	Nuc
Brain	cerebrum	(+)^a	+^b	+^a	+^c
	cerebellum	(+)	-	+	+
Spleen	lymphocytes	-	-	(+)	(+)
	Macrophages^d	++	-	(+)	(+)
Lung	bronchial epithelium	(+)	+	(+)	+
	endothelium	-	+	-	+
	pneumocytes	-	-	-	-
Kidney	glomeruli	-	++ ^e	+^f	+ - ++^g
	tubules	++	-	++	++
	peritubular capillaries	-	++	-	++
Pancreas	exocrine	++	-	++	++
	endocrine	+	-	++	++
Adrenal	cortex	-	-	-	-
	medulla	+	-	++	++
Uterus	endometrial glands	(+)	(+)	(+)	++
	endometrial stroma	-	-	-	(+)
	smooth muscle	-	-	-	(+)
Testes	germ cells	-	-	++	++
	Sertoli cells	-	-	++	++
	Leydig cells	++	++	++	++
Stomach	superficial crypts	-	-	-	-
	deep crypts	(+)	++	-	++
	smooth muscle	-	-	(+)	++
Ilium	glands	++	-	++	++
	ganglia	++	-	++	++
	smooth muscle	-	-	(+)	+
Colon	glands	++	-	++	++
	ganglia	++	-	++	++
	smooth muscle	-	-	(+)	+
Heart		-	-	(+)	+
Liver		+ +	-	+ +	+ +

^a white matter only; ^b oligodendrocytes; ^c oligodendrocytes and neurons; ^d sinusoidal macrophages; ^e glomerular endothelium only; ^f glomerular podocytes; ^g + in glomerular podocytes, ++ in glomerular endothelium.

Back to article page

ISSN: 1471-2199

Contact us

General enquiries: ORSupport@springernature.com