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Table 1 Prediction of Mitochondrial Localization

From: Alternative splicing and differential subcellular localization of the rat FGF antisense gene product

Protein

Program

 

IPSORT (%)

LOCtree

MitoProtII.0a4

TargetPv1.01

hGFGa

yes

no

yes(0.872)

yes(0.864/28)

hGFGb

yes

no

yes(0.306)

no

hGFGc

yes

yes

no

no

rGFG

yes

no

yes(0.901)

yes(0.820/28)

rGFGΔ2

yes

no

yes(0.523)

yes(0.805/28)

rGFGΔ2/3

yes

no

yes(0.602)

yes(0.776/28)

rGFGc

no

no

no

no

murGFG

yes

no

yes(0.980)

yes(0.877/28)

droGFG

yes

yes

yes(0.997)

yes(0.832/32)

chiGFG

yes

yes

yes(0.321)

yes(0.352/20)

xenGFG

no

no

yes(0.334/13)

no

fugGFG

yes

yes

yes(0.999)

yes(0.956/25)

panGFG

yes

yes

yes(0.878)

yes(0.870/28)

ponGFG

yes

yes

yes(0.892)

yes(0.910/28)

dogGFG

yes

yes

yes(0.977)

yes(0.862/28)

mosGFG

yes

yes

yes(0.959)

yes(0.794/28)

atGFG

no

no

no

no

ceNudix1

no

no

no

no

hNUDT9

yes

no

yes(0.478)

yes(0.688/46)

hMTH

yes

yes

yes(0.639)

yes(0.644/34)

hMTY

no

yes

yes(0.501)

yes(0.612/14)

  1. h = human; pan = Pan troglodytes; pon = Pongo pygmaeus. r = Rattus norvegicus (rat); mur = Mus musculus (mouse); dog = Canis familiaris; chi = Gallus gallus (chicken); xen = Xenopus laevis; Tr = Takifugu rubripes; dro = Drosophila melanogaster (fruitfly); At = Arabidopsis thaliana. mos = Anopheles gambiae (malaria mosquito); ce = Caenorhabditis elegans. hGFGa, -b and c represent human GFG isoforms; rGFG, -GFGΔ2,-GFGΔ2/3, and -GFGc indicate known and predicted rat GFG isoforms. yes/no = mitochondrial targeting signal peptide at the N-terminal of the protein has/not been identified; the numbers (ranging from 0.0 to 0.999) in the brackets indicate the probabilities of the predictions. The numbers behind the slashes indicate the predicted cleavage sites of the mitochondrial peptidases.