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Table 2 Genes induced or repressed in MeWo-IE63 cells compared with control cells (MeWo-Inv).

From: The Varicella-Zoster Virus Immediate-Early 63 protein affects chromatin controlled gene transcription in a cell-type dependent manner

Affimetrix designation

Entrez gene no.

Fold Induction

Gene Symbol

Description

Signal Transduction

    

204425_at

393

0.50

ARHGAP4

Rho GTPase activating protein 4

204736_s_at

1464

0.50

CSPG4

chondroitin sulfate proteaoglycan 4

206028_s_at

10461

0.50

MERTK

c-mer proto-oncogene tyrosine kinase

206374_at

1850

0.50

DUSP8

dual specificity phosphatase 8

213221_s_at

23235

0.50

KIAA0781

KIAA0781 protein

206359_at

9021

0.38

SSI-3

STAT induced STAT inhibitor 3

202328_s_at

5310

0.33

PKD1

polycystic kidney disease 1 (autosomal dominant)

Transcription

    

201328_at

2114

0.50

ETS2

avian erythroblastosis virus E26 oncogene homolog 2

213668_s_at

6659

0.50

SOX4

SRY (sex determining region Y)-box 4

213931_at

3398

0.50

ID2

inhibitor of DNA binding 2, dominant negative helix-loop-helix protein

215012_at

26036

0.47

KIAA0576

KIAA0576 protein

31637_s_at

732801

0.47

Rev-ErbAalpha

Rev-ErbAalpha

203873_at

6594

0.44

SMARCA1

Human global transcription activator homologous sequence mRNA

202672_s_at

467

0.41

ATF3

activating transcription factor 3

210426_x_at

6095

0.41

RORA

Human orphan hormone nuclear receptor RORalpha1 mRNA

202861_at

5187

0.38

PER1

Homo sapiens period (Drosophila) homolog 1

Immunity/Inflamation

    

215193_x_at

3125

2.64

HLA-DRB1

MHC class II antigen

216598_s_at

6347

2.46

MCP-1

monocyte chemotactic protein

206569_at

11009

2.14

ST16

Homo sapiens suppression of tumorigenicity 16

211990_at

3113

2.14

HLA-DPA1

MHC class II DPw3-alpha-1 chain mRNA

208894_at

3122

2.00

HLA-DRA

MHC class II HLA-DR-alpha

209312_x_at

3123

2.00

HLA-DRB1

HLA-DRB (MHC class II antigen)

206026_s_at

7130

0.50

TNFAIP6

tumor necrosis factor, alpha-induced protein 6

209447_at

23345

0.50

8B7

lymphocyte membrane associated protein

214201_x_at

7916

0.47

D6S51E

HLA-B associated transcript-2

207850_at

2921

0.44

GRO3

GRO3 oncogene

217028_at

7852

0.38

CXCR4

receptor CXCR4

205599_at

7185

0.35

TRAF1

TNF receptor-associated factor 1

203665_at

3162

0.35

HMOX1

heme oxygenase (decycling) 1

Intracellular organelle

    

217452_s_at

8707

3.73

B3GALT2

2-acetamido-2-deoxy-D-glucose3beta- galactosyltransferase

205069_s_at

23092

2.83

KIAA0621

KIAA0621 protein

219250_s_at

23767

2.30

FLRT3

FLRT3 (fibronectin leucine rich transmembrane protein 3)

211205_x_at

8394

2.14

PIP5K1A

68 kDa type I phosphatidylinositol-4-phosphate5-kinase alpha

205547_s_at

6876

2.00

TAGLN

transgelin

204293_at

6448

0.50

SGSH

N-sulfoglucosamine sulfohydrolase

209893_s_at

2526

0.50

FUT4

ELAM-1 ligand fucosyltransferase

205830_at

1047

0.38

CLGN

Homo sapiens calmegin

207949_s_at

3382

0.33

ICA1

islet cell autoantigen 1 (69 kD)

214341_at

8906

0.02

AP1G2

adaptor-related protein complex 1, gamma 2 subunit

Chromatin

    

212257_s_at

6595

2.00

SMARCA2

SWISNF related actin dependent regulator of chromatin, sf a, mb 2

210387_at

8339

2.00

H2BFA

H2B histone family, member A

Heat-Shock

    

202581_at

3304

0.50

HSPA1B

heat shock 70 kD protein 1B

202843_at

4189

0.47

MDG1

microvascular endothelial differentiation gene 1

217911_s_at

9531

0.47

BAG3

BCL2-associated athanogene 3

117_at

3311

0.27

HSP70B

HSP70B Human heat-shock protein HSP70B gene

213418_at

3310

0.22

HSPA6

heat shock 70 kD protein 6 (HSP70B)

Other/Unclassified

    

204730_at

9783

5.66

KIAA0237

KIAA0237 gene product

206021_at

54581

3.03

SCAND2

SCAN domain-containing 2

222108_at

347902

2.83

AMIGO-2

amphoterin-induced protein 2 precursor

218332_at

55859

2.64

HBEX2

hypothalamus protein

214079_at

10901

2.30

SDR2

dehydrogenase/reductase (SDR family) member 2

208282_x_at

57055

2.00

DAZ2

deleted in azoospermia 2

205960_at

5166

2.00

PDK4

Homo sapiens pyruvate dehydrogenase kinase, isoenzyme 4

211814_s_at

9134

2.00

CCNE2

cyclin E2 splice variant 1

202842_s_at

4189

0.50

DKFZp564F1862

hypothetical protein

222175_s_at

51586

0.50

FLJ00003

FLJ00003 protein

201500_s_at

6992

0.50

PPP1R11

PPP1R11

203045_at

4814

0.50

NINJ1

ninjurin 1

206307_s_at

2297

0.50

FOXD1

forkhead box D1

216594_x_at

1645

0.50

chlordecone

chlordecone reductase homolog

220058_at

79018

0.50

MGC3048

hypothetical protein MGC3048

221213_s_at

54816

0.50

FLJ20086

hypothetical protein FLJ20086

218145_at

57761

0.50

LOC57761

protein kinase domains containing proteinsimilar to phosphoprotein C8FW

219401_at

64132

0.50

XT2

xylosyltransferase II

220587_s_at

64223

0.50

GBL

G protein beta subunit-like

214782_at

11016626

0.47

FLJ13271

cDNA FLJ13271 fis

214814_at

11684382

0.47

DKFZp564P056

cDNA DKFZp564P056

218651_s_at

55323

0.47

FLJ11196

hypothetical protein FLJ11196

219039_at

54910

0.47

FLJ20369

hypothetical protein FLJ20369

221836_s_at

6697854

0.47

FLJ22741

Homo sapiens cDNA: FLJ22741 fis

203431_s_at

9743

0.47

KIAA0712

KIAA0712 gene product

203504_s_at

19

0.47

ABCA1

ATP-binding cassette, sub-family A, member 1

209947_at

9898

0.47

KIAA0144

KIAA0144 gene product

218751_s_at

55294

0.44

FLJ11071

hypothetical protein FLJ11071

215078_at

4914612

0.44

DKFZp564M2422

cDNA DKFZp564M2422

204623_at

7033

0.44

TFF3

Homo sapiens trefoil factor 3 (intestinal)

209182_s_at

11067

0.44

DEPP

decidual protein induced by progesterone

215670_s_at

10434472

0.41

FLJ12782

cDNA FLJ12782 fis

218920_at

54540

0.41

FLJ10404

Homo sapiens hypothetical protein

219747_at

79625

0.41

FLJ23191

Homo sapiens hypothetical protein FLJ23191

204469_at

5803

0.41

PTPRZ1

protein tyrosine phosphatase, receptor-type, Z polypeptide 1

212531_at

3934

0.41

LCN2

Homo sapiens lipocalin 2 (oncogene 24p3)

211030_s_at

13623302

0.38

MGC:10619

clone MGC:10619

221959_at

10032854

0.38

FLJ22488

FLJ22488 fis

209160_at

8644

0.38

c-hluPGFS

Homo sapiens mRNA for hluPGFS

212839_s_at

6738

0.38

SSA2

Sjogren syndrome antigen A2 (60 kD, ribonucleoprotein autoantigen SS-ARo)

218864_at

7145

0.35

PRO0929

PRO0929 mRNA

220123_at

80255

0.35

FLJ22004

hypothetical protein FLJ22004

207992_s_at

272

0.35

AMPD3

adenosine monophosphate deaminase (isoform E)

213158_at

1523376

0.33

DKFZp586B211

cDNA DKFZp586B211

213445_at

23144

0.33

KIAA0150

KIAA0150 protein

219797_at

11320

0.33

MGAT4A

mannosyl-glycoprotein beta-acetylglucosaminyltransferase

219935_at

11096

0.31

ADAMTS5

disintegrin-like and metalloprotease with thrombospondin type 1 motif

213156_at

12761337

0.29

DKFZp586B211

cDNA DKFZp586B211

216006_at

24694

0.27

24694

clone 24694

206273_at

10650

0.27

HFL-EDDG1

erythroid differentiation and denucleation factor 1

218790_s_at

55217

0.19

FLJ10727

hypothetical protein FLJ10727

211037_s_at

13623420

0.07

MGC:13124

clone MGC:13124

210709_at

7770220

0.06

PRO2710

PRO2710 mRNA

209613_s_at

125

0.02

ADH2

alcohol dehydrogenase beta-1 subunit

217177_s_at

5262528

0.01

FLJ13658

cDNA DKFZp564N2216