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Figure 3 | BMC Molecular Biology

Figure 3

From: The Varicella-Zoster Virus Immediate-Early 63 protein affects chromatin controlled gene transcription in a cell-type dependent manner

Figure 3

RNA polymerase II recruitment on selected cellular genes in HeLa cells expressing or not IE63. ChIP assay using RNA polymerase II antibody or unspecific antibody (lane 1) was performed on total cell lysates. Real-time PCR amplification of a 100 bp fragment from the WIF1 (A), and C3 (B) promoter encompassing [59] the transcription initiation site was carried out. ρ-values were calculated using the graphpad quickcalcs software [59]: *, significantly different from control (Inv ; p-value < 0.05).

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