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Table 1 The kinetics of equimolar mixture of human plasmin with RGD-SAK

From: Characterization of a novel bifunctional mutant of staphylokinase with platelet-targeted thrombolysis and antiplatelet aggregation activities

 

Km (μM)

kcat (s-1)

kcat/Km (μM-1s-1)

SAK

0.39 ± 0.03

0.015 ± 0.002

0.033 ± 0.003

RGD-SAK

0.78 ± 0.05

0.031 ± 0.001

0.037 ± 0.005

  1. Data obtained from three experiments.