Human (bp) | Chimpanzee Score (bp) | Macaque Score (bp) | Dog Score (bp) |
---|
Exon 2 (84) | 98 (84) | 97 (84) | 85 (84) |
Exon 2a (641) | 98 (641) | 95 (639) | 82 (622)†|
Exon 2b (119) | 99 (119) | 74 (122) | - |
Exon 2c (883) | 98 (852) | -* | 77 (507)†|
Exon 2d (312) | - | - | - |
Exon 2e (115) | 99 (129) | 89 (66)†| 58 (141)‡ |
Exon 3 (96) | 99 (96) | 95 (84)†| 39 (103)‡ |
Coding exons | 99 | 95 | 91 |
- Identity scores were calculated by ClustalW alignments and include scores for the novel human PPARδ exons and human exon 2, exon 3 and coding exons (1326 bp) for comparison. Exon 1 was not included since complete sequence information for this exon is not available for all species. Scores given in italic numbers indicate a sequence without conserved splice junctions.
- * Sequence comparison precluded by unsequenced gaps in the macaque PPARδ gene
- †A full-length exon is not conserved. Identity scores are given for a sequence homologous to the 3'-region of the comparable human exon
- ‡ An orthologous exon was not identified. Identity scores are given for a sequence with the highest homology scores within the genomic region comparable to the location of the human exon