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Table 4 Sequence identity scores of human PPARδ exons in comparable regions of orthologous genes

From: Alternative splicing of human peroxisome proliferator-activated receptor delta (PPARdelta):effects on translation efficiency and trans-activation ability

Human (bp) Chimpanzee Score (bp) Macaque Score (bp) Dog Score (bp)
Exon 2 (84) 98 (84) 97 (84) 85 (84)
Exon 2a (641) 98 (641) 95 (639) 82 (622)†
Exon 2b (119) 99 (119) 74 (122) -
Exon 2c (883) 98 (852) -* 77 (507)†
Exon 2d (312) - - -
Exon 2e (115) 99 (129) 89 (66)† 58 (141)‡
Exon 3 (96) 99 (96) 95 (84)† 39 (103)‡
Coding exons 99 95 91
  1. Identity scores were calculated by ClustalW alignments and include scores for the novel human PPARδ exons and human exon 2, exon 3 and coding exons (1326 bp) for comparison. Exon 1 was not included since complete sequence information for this exon is not available for all species. Scores given in italic numbers indicate a sequence without conserved splice junctions.
  2. * Sequence comparison precluded by unsequenced gaps in the macaque PPARδ gene
  3. †A full-length exon is not conserved. Identity scores are given for a sequence homologous to the 3'-region of the comparable human exon
  4. ‡ An orthologous exon was not identified. Identity scores are given for a sequence with the highest homology scores within the genomic region comparable to the location of the human exon