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Table 4 Sequence identity scores of human PPARδ exons in comparable regions of orthologous genes

From: Alternative splicing of human peroxisome proliferator-activated receptor delta (PPARdelta):effects on translation efficiency and trans-activation ability

Human (bp)

Chimpanzee Score (bp)

Macaque Score (bp)

Dog Score (bp)

Exon 2 (84)

98 (84)

97 (84)

85 (84)

Exon 2a (641)

98 (641)

95 (639)

82 (622)†

Exon 2b (119)

99 (119)

74 (122)

-

Exon 2c (883)

98 (852)

-*

77 (507)†

Exon 2d (312)

-

-

-

Exon 2e (115)

99 (129)

89 (66)†

58 (141)‡

Exon 3 (96)

99 (96)

95 (84)†

39 (103)‡

Coding exons

99

95

91

  1. Identity scores were calculated by ClustalW alignments and include scores for the novel human PPARδ exons and human exon 2, exon 3 and coding exons (1326 bp) for comparison. Exon 1 was not included since complete sequence information for this exon is not available for all species. Scores given in italic numbers indicate a sequence without conserved splice junctions.
  2. * Sequence comparison precluded by unsequenced gaps in the macaque PPARδ gene
  3. †A full-length exon is not conserved. Identity scores are given for a sequence homologous to the 3'-region of the comparable human exon
  4. ‡ An orthologous exon was not identified. Identity scores are given for a sequence with the highest homology scores within the genomic region comparable to the location of the human exon