Alternative splicing of human peroxisome proliferator-activated receptor delta (PPARdelta):effects on translation efficiency and trans-activation ability

Table 1 Sequences of splice junctions of newly identified spliced-in exons in the 5'-UTR of human PPARδ

Spliced-in exon	Size (bp)	Genomic position downstream of exon 2 (bp)	3'-splice acceptor	5'-splice donor
2a	641	1212	ctgcag GGGTAG	TCGCAGgt agga
2b	119	4427	agatag CATCTC	CTACAGgt atgt
2c	122	5778	tctcag GACCAG	TGTGAGgt aatg
2d	315	36426	atctag GAGGTG	TGGGAAgt gagg
2e	115	49826	tttcag ATTATC	TGTCCTgt gagt

The genomic positions of exons were deduced using the human PPARδ RefSeq [GenBank: NM_006238]. Upper-case and lower-case letters indicate exon and intron sequences, respectively. The consensus splice donor-acceptor sequences are in bold letters.

ISSN: 1471-2199