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Figure 9 | BMC Molecular Biology

Figure 9

From: Alternative splicing of human peroxisome proliferator-activated receptor delta (PPARdelta):effects on translation efficiency and trans-activation ability

Figure 9

Conservation profiles of the PPARδ gene using the ECR Browser tool. The conservation profiles (percent identity cut-off of 50% to 100%) of the human PPARδ gene in comparison with the mouse (Mus musculus; chr17), dog (Canis familiaris; chr12), macaque (Macaca mulatta; chr4) and chimpanzee (Pan troglodytes; chr6) orthologous genes are shown. Conserved sequences are defined as coding exons (blue), untranslated exons (yellow) and introns (pink). The locations of the novel untranslated human exons (2a-2e) in the PPARδ gene are indicated by arrows. The percent identity of the masked (unaligned) sequence harbouring exons 2b and 2c obtained by ClustalW alignment is indicated in the defined area, likewise the lack of identity over the masked region containing exon 2d is indicated by horizontal lines. A schematic view showing the locations of previously identified exons in human PPARδ gene are aligned above the conservation profile for orientation.

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