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Figure 6 | BMC Molecular Biology

Figure 6

From: Inactivation of nucleolin leads to nucleolar disruption, cell cycle arrest and defects in centrosome duplication

Figure 6

Depletion of nucleolin induces hyper amplification of centrosome and multipolar mitotic spindle formation. HeLa cells transfected for 4 days with control siRNA # 1 or with the nucleolin siRNA mix #2 and #4 were processed for immunofluorescence. Centromeres were stained with a CREST antiserum (CEN), microtubules with an α-tubulin antibody, centrosomal structures with a γ-tubulin antibody and DAPI was used to counterstained DNA. Views of 3D reconstructions are shown for each label and for merged labels as indicated.

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BMC Molecular Biology

ISSN: 1471-2199

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