From: Somatic CTG•CAG repeat instability in a mouse model for myotonic dystrophy type 1 is associated with changes in cell nuclearity and DNA ploidy
Age*
1 – 3 months
12 – 25 months
Somatic Expansion
no
yes
Ploidy
2n
4n
8n
54 ± 9%
45 ± 8%
2 ± 2%
45 ± 5%
43 ± 3%
13 ± 3%
Nuclearity
100% mononuclear
80% binuclear
n.d.