Figure 4
From: An improved genetic system for detection and analysis of protein nuclear import signals
Analysis of nuclear import mediated by various regions of E1A. A) Map of the 289 residue human adenovirus type 5 E1A protein, previously identified regions known to confer nuclear import and constructs used in this study. The indicated amino acid numbers are inclusive. B) Effects of the various indicated E1A regions on nuclear import in yeast as measured with the β-galactosidase reporter. In each case, the corresponding empty control vector was arbitrarily set at a value of 1, whereas bars shaded in black represent the original ratios (means ± SD, n = 3). Lightly shaded bars indicate values normalized to protein expression.