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Table 1 Summary of transcriptional changes following gene transfer by electroporation

From: Gene expression profiles in skeletal muscle after gene electrotransfer

Gene Ontology

EP

DNA

Time

Metabolism

   

phosphoenolpuryvate carboxykinase 2

↓

0

0

dipeptidase

↓

0

0

protein phosphatase 6

0

↓

0

Cytoskeleton

   

sarcospan

↓

0

0

microtubule-associated protein 7

↓

0

0

cadherin-like 26

↓

0

0

junction adhesion molecule 4

↓

0

0

Transcriptional regulation

   

Ephrin

↑

0

0

Forkhead box P1

↓

0

0

F-box and leucine-rich repeat protein

↓

0

0

ring finger protein 184

↓

0

0

splicing factor (SRp75)

0

0

↑

Transducer of ERBB2

0

0

↓

eukaryotic translation initiation factor

0

0

↓

host cell factor C1

0

0

↓

CCR4-NOT transcription complex

0

0

↓

cytoplasmic polyadenylation element

0

0

0

MAPKK3

0

↓

0

polymerase II

0

↓

0

Ca2+ regulation

   

Reticulocalbin 2

0

↓

0

FK506 binding protein 1a

0

↓

0

Intracellular transport

   

ADP-ribosylation factor-like 6 and 10

0

↓

↓

ubiquitin-like 1 (sentrin)

0

↓

0

nuclear transport factor 2

0

↓

0

Membrane transport

   

Chloride channel Ka

0

0

↑

Kruppel-like factor 15

0

0

↓

K+ voltage gated channel, Shab related

0

0

↓

Solute carrier family 6

0

0

↓

ATP-binding cassette (ABC1)

0

0

↓