Table 1 Frequency of base replacement changes in the sequence-based screen
From: Mutational pattern and frequency of induced nucleotide changes in mouse ENU mutagenesis
Base change | Â | Â | Â | |
|---|---|---|---|---|
From | To | k | L | μ × 107 (95%CI) |
T | C | 31 |  | 6.49 (4.58 – 9.21) |
|  | A | 21 |  | 4.39 (2.88 – 6.72) |
|  | G | 5 |  | 1.05 (0.46 – 2.44) |
Subtotal | 57 | 47,799,305 | 11.92 (9.21 – 15.45) | |
C | T | 18 |  | 4.24 (2.69 – 6.70) |
|  | A | 6 |  | 1.41 (0.66 – 3.07) |
|  | G | 0 |  | 0.00 (0.00 – 0.71) |
Subtotal | 24 | 42,475,136 | 5.65 (3.81 – 8.41) | |
A | T | 8 |  | 1.73 (0.89 – 3.40) |
|  | C | 2 |  | 0.43 (0.13 – 1.56) |
|  | G | 18 |  | 3.89 (2.47 – 6.14) |
Subtotal | 28 | 46,311,939 | 6.05 (4.20 – 8.74) | |
G | T | 6 |  | 1.35 (0.63 – 2.94) |
|  | C | 1 |  | 0.22 (0.05 – 1.25) |
|  | A | 14 |  | 3.15 (1.89 – 5.29) |
Subtotal | 21 | 44,445,267 | 4.72 (3.10 – 7.22) | |
Total |  | 130 | 181,031,647 | 7.18 (6.05 – 8.53) |