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Figure 6 | BMC Molecular Biology

Figure 6

From: Novel in vivo targets of ΔNp63 in keratinocytes identified by a modified chromatin immunoprecipitation approach

Figure 6

ΔNp63α activates the ChIPed DNA sequences in reporter gene assays. Luciferase constructs containing the various ChIPed DNA sequences cloned upstream of a heterologous TK promoter demonstrate high levels of activity when co-transfected with an expression plasmid encoding ΔNp63α in PtK2 cells. Luciferase values were determined and normalized against β-galactosidase values. Corrected luciferase values for cells transfected with empty vector pCMV-HA were set at 1. TK; thymidine kinase

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