Figure 1

A schematic representation of the modified chromatin immunoprecipitation approach used to identify potential target genes of ΔNp63. Following chromatin immunoprecipitation, to enrich for ΔNp63 targets, ChIP products were ligated to linkers and amplified by PCR using the linker sequence for priming. The PCR-amplified products were subsequently incubated with agarose beads containing GST-ΔNp63 protein. ChIPed fragments were then digested with Hind III, cloned, and sequenced.