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Figure 3 | BMC Molecular Biology

Figure 3

From: Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition

Figure 3

ATM is activated by PARP inhibitors. Immunostaining for γ-H2AX in G361 (ATM wild type) and HT144 (ATM deficient) cells exposed to γ-irradiation (positive control) or ANI (time course after drug exposure). H2AX (green signal) is phophorilated by ATM after ANI treatment in absence of γ-irradiation in G361 cells (ATM-proficient). DAPI is shown in blue and both views are in coincidence.

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BMC Molecular Biology

ISSN: 1471-2199

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