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Table 1 Copy number and genomic organization of core histone genes

From: Core histone genes of Giardia intestinalis: genomic organization, promoter structure, and expression

   Chromosome2   Poly(A)   Conserved sequences5
Histone ORF ID1 # Position Dir.   Sequence3 STOP4   Upstream Coding Downstream
H4-i 135001 5 0.6 R   AGTAAAC -5 bp   99 bp 300 bp 124 bp
H4-ii 135002 5 0.6 F        
H4-iii 135003 5 0.6 R        
H3-i 135231 4 0.2 R   AG TAA AC overlap   50 bp 441 bp 5 bp
H3-ii 14212 4 0.7 R        
H2a-i 27521 3 0.15 F   TGTAAAC -10 bp   80 bp (-2) 375 bp (-7) 12 bp (-1)
H2a-ii 14256 5 0.6 R   TGTGAAC -20 bp     
H2b-i 121046 5 1.2 R   AG TAA AT overlap   56 bp 393 bp 16 bp
H2b-ii 121045 5 1.2 R        
  1. 1 ORF ID as assigned for each gene on Giardia DB [3].
  2. 2 The chromosome position indicates the distance in Mb from the end of the map for that chromosome. The distance from the telomere is greater, since the map does not extend all the way to the telomeres.
  3. 3 Sequence matching the consensus polyadenylation signal for Giardia genes (Reviewed in [15]); the DNA sequence for the stop codon is underlined in the polyadenylation sequence shown for the H2B and H3 genes since these sequences overlap for these two genes.
  4. 4 Location of putative polyadenylation signal relative to the translation stop codon of each gene.
  5. 5 Coding and non-coding sequences conserved among all copies of each core histone gene; number of nucleotide mismatches are indicated in brackets.