Figure 4

Sequence analysis of the intergenic region of the divergent PDCD10 - SERPINI1 gene pair. Dot matrix alignment of the intergenic sequence of the human PDCD10-SERPINI1 pair with those of mouse (A) and rat (B). The units in both vertical and horizontal axis are the position numbers of the nucleotides in the intergenic region as shown in Fig. 3A. C) The complete nucleotide sequence of the intergenic spacer between human PDCD10 and SERPINI1. The putative transcription factor binding sites are underlined. The transcriptional start sites confirmed by 5'-RACE are indicated by bended arrows. The shaded nucleotides indicate the transcriptional start sites of the reference sequence reported by the NCBI database. The arrowheads indicate the cutting sites for the deletion assays described in Fig. 5.