Table 2 Sequence diversity in cDNA sets#
Pre-injection | Post-injection | Total | Diversity Score | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Challenge | Animal | cDNA Pattern | # of clones | unique clones | dn/ds | Div. score | # of clones | unique clones | dn/ds | Div. score | # of clones | unique clones | dn/ds | Div. score | Pre | Post | Total |
LPS | 1 | E2 | 4 | 3 | 0.93 | 0.002 | 28 | 12 | 0.88 | 0.009 | 32 | 14 | 0.50 | 0.010 | |||
2 | C1 | 10 | 9 | 1.87 | 0.012 | · | · | · | · | · | · | · | · | ||||
3 | E3 | · | · | · | · | 6 | 5 | 0.22 | 0.003 | · | · | · | · | 0.365 | 0.216 | 0.325 | |
C1 | 12 | 8 | 0.36 | 0.005 | · | · | · | + | 15 | 10 | 0.63 | 0.007 | |||||
E2 | · | · | · | · | 8 | 7 | 0.78 | 0.012 | · | · | · | · | |||||
β-1,3-glucan (Lam) | 2 | E2 | 6 | 6 | 1.00 | 0.007 | 32 | 15 | 1.16 | 0.009 | 38 | 20 | 1.47 | 0.010 | |||
E2.1 | 8 | 3 | 0.54 | 0.005 | · | · | · | + | 10 | 4 | 0.72 | 0.007 | |||||
6 | 1 | · | · | · | · | 3 | 3 | 0.46 | 0.003 | · | · | · | · | ||||
E2 | · | · | · | · | 33 | 20 | 0.77 | 0.009 | · | · | · | · | 0.287 | 0.320 | 0.323 | ||
7 | E2 | 7 | 4 | 0.72 | 0.007 | 7 | 7 | 0.49 | 0.008 | 14 | 9 | 0.55 | 0.009 | ||||
E2.1 | 39 | 12 | 0.42 | 0.007 | 37 | 12 | 0.50 | 0.009 | 76 | 19 | 0.47 | 0.006 | |||||
dsRNA | 2 | E2 | 9 | 8 | 0.73 | 0.011 | 12 | 8 | 0.91 | 0.014 | 21 | 14 | 0.88 | 0.017 | |||
E2.1 | 21 | 7 | 0.96 | 0.006 | 19 | 4 | 0.24 | 0.002 | 40 | 10 | 0.62 | 0.004 | |||||
8 | E2 | 2 | 2 | · | + | 8 | 6 | 0.97 | 0.008 | 10 | 7 | 0.82 | 0.008 | ||||
E2.1 | 44 | 19 | 0.72 | 0.01 | 28 | 10 | 1.00 | 0.008 | 72 | 28 | 0.93 | 0.007 | 0.198 | 0.336 | 0.231 | ||
9 | D1 | 3 | 3 | 0.15 | 0.002 | · | · | · | + | 5 | 5 | 0.49 | 0.003 | ||||
E2 | 9 | 9 | 1.00 | 0.005 | 9 | 7 | 0.87 | 0.007 | 18 | 14 | 1.14 | 0.008 | |||||
E2.1 | 30 | 8 | 0.79 | 0.007 | 29 | 8 | 1.00 | 0.007 | 59 | 15 | 1.03 | 0.009 | |||||
aCF | 4 | D1 | · | · | · | · | 5 | 5 | 0.71 | 0.023 | · | · | · | · | |||
E2 | · | · | · | + | 19 | 16 | 1.16 | 0.014 | 20 | 17 | 1.00 | 0.015 | |||||
E2.1 | · | · | · | + | 5 | 4 | 1.00 | 0.002 | 10 | 4 | 1.00 | 0.002 | |||||
0.328 | 0.337 | 0.370 | |||||||||||||||
5 | C1 | 9 | 8 | 1.70 | 0.006 | · | · | · | · | · | · | · | · | ||||
D1 | · | · | · | · | 5 | 5 | 0.99 | 0.015 | · | · | · | · | |||||
E2 | · | · | · | · | 5 | 4 | 1.00 | 0.004 | · | · | · | · | |||||