Table 2 Rates of unequal SCE in various genetic backgrounds.
Genotype | SCE rate for his3-SCS control (× 106) | Relative rate | SCE rate for his3-SCSpal 140(x106) | Relative rate |
|---|---|---|---|---|
aWild type | 0.72 ± 0.06 | 1.0 | 6.66 ± 0.44 | 1.0 |
sgs1 | 9.95 ± 1.50 | 13.8 ↑ (P < 0.0001) | 71.3 ± 8.44 | 10.7 ↑ (P < 0.0001) |
srs2 | 2.38 ± 0.64 | 3.30 ↑ (P < 0.0001) | 13.4 ± 2.24 | 2.01↑ (P = 0.0001) |
mus81 | 1.18 ± 0.20 | 1.64 ↑ (P = 0.0005) | 8.64 ± 1.19 | 1.30 ↑ (P = 0.006) |
a exo1 | 2.80 ± 0.67 | 3.88 ↑ (P < 0.0001) | 26.9 ± 5.93 | 4.03 ↑ (P < 0.0001) |
b rad51 | 1.36 ± 0.38 | 1.90 ↑ (P < 0.0001) | 2.70 ± 0.20 | 0.40 ↓ (P < 0.0001) |
b rad52 | 0.16 ± 0.02 | 0.22 ↓ (P < 0.0001) | 0.58 ± 0.02 | 0.08 ↓ (P < 0.0001) |
a msh2 | 1.87 ± 0.33 | 2.59 ↑ (P < 0.0001) | 4.18 ± 0.46 | 0.62 ↓ (P < 0.0001) |
sgs1 rad51 | 4.53 ± 1.07 | 6.29 ↑ (P < 0.0001) | 13.7 ± 2.68 | 2.06 ↑ (P = 0.0002) |
sgs1 rad52 | 1.32 ± 0.76 | 1.8 ↑ (P = 0.050) | 0.75 ± 0.18 | 0.11 ↓ (P < 0.0001) |
sgs1 exo1 | 21.8 ± 3.36 | 30.27 ↑ (P < 0.0001) | 150 ± 13.0 | 22.52 ↑ (P < 0.0001) |
sgs1 msh2 | 10.0 ± 2.66 | 13.9 ↑ (P < 0.0001) | 35.3 ± 6.05 | 5.30 ↑ (P < 0.0001) |