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Figure 7 | BMC Molecular Biology

Figure 7

From: Interleukin-4 inhibition of interleukin-1-induced expression of matrix metalloproteinase-3 (MMP-3) is independent of lipoxygenase and PPARγ activation in human gingival fibroblasts

Figure 7

PPAR antagonist GW9662 fails to reverse the inhibitory effects of IL-4. HGF cultures were pre-treated with GW9662 at the indicated doses for one hour before addition of IL-1 (10 ng/ml) and/or IL-4 (10 ng/ml). Total RNA was isolated at 12 hours, quantitated by real-time PCR and normalized to levels of GAPDH. The graph represents data from six independent experiments performed in triplicate, mean +/- SEM. Statistical significance was determined by Students T-test.

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BMC Molecular Biology

ISSN: 1471-2199

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