Checkpoint independence of most DNA replication origins in fission yeast

BMC Molecular Biology

Table 1 The data from Additional File 7 applicable to Figure 2.

Start Position	End Position	Start Gene	End Gene	AT Number	AT Function	Feng et al. WT Function	Feng et al. cds1 Function	Heichinger et al. Number	Heichinger et al. Efficiency	Hayashi et al. PreRC Number	Hayashi et al., Activity	Mickle et al. Function
3989260	3993040	SPAPB15E9.01c	SPAPB15E9.02c					Ori1129	59	1148	1	strong
3993040	3997640	SPAPB15E9.02c	SPAPB15E9.03c	AT1129	strong	strong	strong			1149	1	strong
4003300	4005680	SPAC27E2.01	SPAC27E2.02									medium
4007292	4010577	SPAC27E2.03c	SPAC27E2.11c							1150	0	weak
4017870	4021600	SPAC27E2.06c	pvg2	AT1130	strong	strong	strong	Ori1130	31	1151	1	strong

This table displays a small subset (only the information relevant to Fig. 2) of the information contained in Additional File 7. For each of the putative origins identified and evaluated in Fig. 2, the first two columns of Table 1 show the start (left side) and end (right side) of the positions of the PCR probes located in the genes flanking the origin. The next two columns show the names of those two genes (which are also shown in Fig. 2). Where the origin being evaluated is an AT island, the next two columns show the name of the AT island (according to [20]) and its functional classification by our criteria (see Methods). The following two columns show the classification of origins identified by Feng et al. in wild-type or in cds1 Δ cells. For origins identified by Heichinger et al., the following two columns show the Ori number assigned to the origin and the efficiency of the origin during a mitotic S phase as evaluated by Heichinger et al. [14]. For pre-RCs identified by Hayashi et al. [15], the next two columns show the number of the pre-RC and whether the pre-RC was scored by Hayashi et al. as strong/early (1) or weak/late (0). The final column shows our (Mickle et al.) classification of the putative origin.

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