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Figure 4 | BMC Molecular Biology

Figure 4

From: Checkpoint independence of most DNA replication origins in fission yeast

Figure 4

AT islands correlate with strong potential origin activity. The signals from the probes flanking the 387 AT island positions were evaluated and assigned to one of the five categories (below limit to strong; horizontal axis), and the percentage of AT islands in each of the five categories was determined (magenta bars; vertical axis). Similarly, the percentages of signals in each category from the 4636 pairs of adjacent probes that did not flank AT islands were also plotted (blue bars). To obtain the randomized results (cream-colored bars), the six datasets (wild-type, cds1 Δ, and rad3 Δ at 2 and 4 hours) were randomized for position within each dataset, and the scores for all positions were re-calculated. This was repeated ~1000 times, and the resulting average percentages are shown.

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