Figure 4
From: Hepatoma derived growth factor binds DNA through the N-terminal PWWP domain
HDGF protect DNA from DNase I digestion. DNase I footprinting analysis of the 80 bp DNA fragment using GST-HDGF recombinant protein. The DNA fragment is the same as the probe used in EMSA corresponding to nucleotides -688 to -609 of the SMYD1 gene promoter. Numbers on the left side indicate the location in the SMYD1 promoter. Protected sequence is indicated with single line.