Figure 1
From: Hepatoma derived growth factor binds DNA through the N-terminal PWWP domain
Alignment of ChIP clones identify a HDGF binding motif consensus with the SMYD1 gene promoter. ChIP was carried out as described in method. Totally 100 clones were sequenced, and 10 of them share a conserved region. The figure shows that these 10 clones were aligned with human SMYD1 gene promoter homologue region using ClustalW program. The genomic and chromosome location were indicated at the beginning and ending of each sequences. The solid line indicates the sequence of the 80 bp probe for EMSA.