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Figure 1 | BMC Molecular Biology

Figure 1

From: The in vitro real-time oscillation monitoring system identifies potential entrainment factors for circadian clocks

Figure 1

Screening of entrainment factors by using IV-ROMS. mPer2-luc/Rat1 cells were monitored the luciferase intensity for duration of 3 days using IV-ROMS. Figure 1A shows luciferase activity after 1 h treatment with 50% serum (positive control, left panel) or DMSO (negative control, right panel). Figure 1B shows luciferase activity after 1 h treatment with 1 or 10 μM of each of the 12 possible circadian entrainment factors. A representative result was chosen out of three independent experiments. Abscissa presents "day", ordinate "relative luciferase intensity", respectively. The first peak was set to 1.

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