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Table 1 Sequence identity of conserved motifs of omTERT to different vertebrate TERT proteins

From: Hypoxia induces telomerase reverse transcriptase (TERT) gene expression in non-tumor fish tissues in vivo: the marine medaka (Oryzias melastigma) model

Motif

Overall cross-species identity (%)

Percent sequence identity of omTERT and:

  

gTERT

fTERT

xTERT

cTERT

hTERT

mTERT

N-terminal region

Region v-I

10.2

54.3

52.6

28.0

23.8

27.9

29.0

Region v-II

8.3

71.9

62.5

22.5

27.8

25.0

23.1

Region v-III

25.7

68.6

62.9

42.9

37.1

45.7

37.1

Region v-IV

25.0

75.8

69.5

43.3

42.7

41.9

42.7

Central region

T motif

33.3

70.8

77.1

39.6

37.5

39.6

43.8

RT motifs:

       

Motif 1

28.0

77.3

77.3

35.7

39.3

40.0

31.0

Motif 2

6.1

54.5

63.6

15.6

15.8

22.9

21.9

Motif A

29.4

82.4

70.6

50.0

47.1

50.0

41.2

Motif B'

47.1

94.1

82.4

52.9

58.8

64.7

58.8

Motif C

58.8

88.2

82.4

76.5

70.6

70.6

70.6

Motif D

34.6

76.9

80.8

57.7

53.8

57.7

53.8

Motif E

63.6

100.0

90.9

90.9

66.7

90.9

100.0

C-terminal region

Region v-V

38.1

100.0

90.5

66.7

61.9

61.9

52.4

Region v-VI

47.2

83.3

79.2

54.2

54.2

58.3

56.9

Region v-VII

11.8

64.9

63.4

25.3

24.7

28.0

28.4