Characterization of novel alternative splicing sites in human telomerase reverse transcriptase (hTERT): analysis of expression and mutual correlation in mRNA isoforms from normal and tumour tissues

Table 2 Statistical correlation between hTERT ASPSs ¹⁾

	Ins-i2 [1–349]	Ins-i2 [182–349]	Ins-i2 [?–5273]	Ins-i4 [1–38]	Del-e6 [1–36]	Del-e7e8
Ins-i4 [1–38]	-0.12	-0.04	0.51
Del-e6 [1–36]	-0.14	-0.04	0.32	0.34
Del-e7e8	0.28	-0.09	-0.03	-0.22	-0.10
Ins-i14 [623–781]	-0.08	-0.02	0.42	0.44	0.30	-0.12
Ins-i14 [623–705]	0.63	-0.02	-0.09	-0.09	-0.10	0.14
Ins-i14 [623–703]	-0.02	-0.01	-0.04	-0.04	-0.04	-0.09
Ins-i14	-0.03	-0.01	-0.05	-0.05	-0.06	0.12

¹⁾ Correlation coefficient calculated according to the formula: ρ_{X, Y} = cov(X, Y)/(σ_X·σ_Y), where σ_x² = Σ(X_i-μ_x)²/n, σ_y² = Σ(Y_i-μ_y)²/n (ρ; correlation coefficient, cov; co-variance, σ; standard deviation). The correlation coefficient is a number between -1 and 1: -1, mutually exclusive (all clones contain one or the other); 0, random distribution or both not present; 1, always occur together (independently of frequency).

ISSN: 1471-2199