Skip to main content
Figure 6 | BMC Molecular Biology

Figure 6

From: Multiple erythroid isoforms of human long-chain acyl-CoA synthetases are produced by switch of the fatty acid gate domains

Figure 6

Gate (A) and linker (B) domains of human acyl-CoA synthetase family members. The Y residue of the Gate domain for long and very-long-chain ACS is boxed. The D and G residues of the Linker domains are boxed. GenBank accession numbers for short, medium, long and very-long chain are indicated on the left. The Gate domain of BG1 is of the long-chain type but its Linker is of the short-medium type. Lipidosin is a soluble ACS very-long-chain isoform found in brain tissue and is known to have a broader substrate range than other very-long ACS [17, 18].

Back to article page