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Figure 4 | BMC Molecular Biology

Figure 4

From: Multiple erythroid isoforms of human long-chain acyl-CoA synthetases are produced by switch of the fatty acid gate domains

Figure 4

Genomic and amino acid sequences of the gate-domain region of human ACSL6 and ACSL1. A and B: Sequence of exons and introns of human ACSL6 (A) and ACSL1 (B) are represented by capitalized and small italics letters, respectively. The F and Y residues of the Gate domain of variant 2 and 1, respectively, are boxed. C: Amino acids alignment of the Gate-domain motifs for known and predicted spliced variants. Highly conserved residues are shaded. Position of the first and last residues shown is indicated on the left and right, respectively. Abbreviations are: Hs, Homo sapiens; Ms, Mus musculus; Pt, Pan troglodytes.

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