Figure 2

Details of the sequence differences of the five human ACSL6 isoforms. The Y and F residues of the Gate domains are boxed. Position of the first and last residues shown is indicated on the left and right, respectively. Note that only the Gate-domain region of ACSL6_v4 is known. A predicted transmembrane spanning segment at the amino-terminus is shown underlined. The inserted sequence in between Exon 7 and Exon 9 of variant 5, annotated as Exon 8, is shown double-underlined.