Figure 3From: No direct effect of the -521 C/T polymorphism in the human dopamine D4 receptor gene promoter on transcriptional activityThe effect of 5' deletions on the transcriptional activity of the DRD4 promoter in four different cell lines. Significant difference in promoter activity of pDRD4-A could be observed in each cell line relative to construct B (P < 0.001). Luciferase activity was normalized to the β-galactosidase activity. Data are expressed as fold increments over the pGL3-Basic activity and shown as mean ± SD. Results of a representative experiment are shown as measured in triplicates (*P < 0.05, **P < 0.01, ***P < 0.001 versus the corresponding promoterless vector in each cell type.) Similar data were obtained from three independent transfection experiments.Back to article page